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SME IV

Significance, Inc.
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Sep 21, 2026

At Significance, we believe the best results come from investing in great people. As a woman-owned consulting firm supporting federal civilian and Department of Defense customers, we bring together talented professionals who are passionate about solving complex challenges and making a meaningful impact.

We're proud of the culture we've built - one rooted in trust, collaboration, respect, and genuine relationships. Our people are empowered to share ideas, grow their careers, and deliver exceptional results while supporting missions that matter. It's a culture we're proud of, and one that has earned us recognition as a Washington Business Journal Best Place to Work for seven consecutive years.

At Significance, we believe the best results come from investing in great people. As a woman-owned consulting firm supporting federal civilian and Department of Defense customers, we bring together talented professionals who are passionate about solving complex challenges and making a meaningful impact.

We're proud of the culture we've built - one rooted in trust, collaboration, respect, and genuine relationships. Our people are empowered to share ideas, grow their careers, and deliver exceptional results while supporting missions that matter. It's a culture we're proud of, and one that has earned us recognition as a Washington Business Journal Best Place to Work for seven consecutive years.


Significance is seeking Chemical and Biological Defense Program (CBDP) Functional Subject Matter Expert (SME) for an anticipated federal program. This role requires collaboration across accounting, budget, and compliance functions and includes responsibility for Enterprise Risk Management (ERM), internal controls, audit readiness, funds management, and financial systems integration. 
  • Provide CBDP program support for all aspects of accounting, financial reporting, and internal controls.
  • Lead implementation and monitoring of Enterprise Risk Management (ERM) and support development of the Manager’s Internal Control (MIC) Program.
  • Support Information System Controls, including Complementary User Entity Controls (CUECs), and ensure compliance with federal requirements.
  • Conduct reconciliation of budgetary and proprietary accounts and monitor vendor pay operations.
  • Provide expertise in funds management and control, ensuring accuracy and audit readiness of CBDP transactions.
  • Support financial systems integration and coordination, including DAI, JICAP, and related platforms.
  • Prepare audit documentation, corrective action plans, and sustainment strategies in line with GAO, OMB, and DoD standards.
  • Develop and deliver financial management reports, metrics, and briefings to senior leadership

Required Skills:

  • Previous experience directly supporting Defense Threat Reduction Agency (DTRA) highly preferred
  • Bachelor’s Degree in Business, Finance, Accounting, or related field
  • Minimum 10+ years of progressively responsible experience in financial management, internal controls, or enterprise risk management
  • Demonstrated experience in quantitative/qualitative analysis, ERM implementation, and financial compliance in federal environments
  • Active Secret security clearance (Top Secret/SCI preferred)


At Significance, your base pay is one part of your total compensation package and is determined within a range. Our pay ranges are based on the local cost of labor benchmarks for each specific role, level, and geographic location.
We carefully consider a wide range of factors when determining compensation, including but not limited to experience; job-related skill sets; relevant education or training; and other business and organizational needs. The salary range listed is for the level at which this job has been scoped. In the event that you are considered for a different level, a higher or lower pay range would apply. This position is also eligible for a comprehensive and generous benefits package.
We are an E-Verify Employer

Job ID

f5c53491-ee0e-4465-9dfa-9a4050e3f3ac

Security Clearance

SECRET
About Significance, Inc.
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